ea0086p129 | Reproductive Endocrinology | SFEBES2022
Zhou Guannan
, Gu Yuanyuan
, Zhou Fangyue
, Hua Keqin
, Ding Jingxin
Background: Adipocyte cells could produce numerous extracellular vesicles and orchestrate the balance of endocrinological system. Polycystic ovary syndrome (PCOS) is a refractory reproductive disease and also a kind of endocrine and metabolic disease. The aim of the study was to explore the effects of adipocyte-derived extracellular vesicles-miR-26b on cumulus cells (CCs) and development of PCOS.Methods: The crosstalk mediated by extracellular vesicle-mi...